トピックス

ニューロサイエンスの旅 Vol. 68

当科の堀 聡先生の椎骨動脈解離に関する論文がJournal of Stroke and Cerebrovascular Diseases誌に掲載されました。椎骨動脈の左右差、椎骨動脈-脳底動脈合流部の外方偏位が椎骨動脈解離の解剖学的要因になり得るという報告です。

A Voyage to Depth of Neuroscience Vol. 68

Anatomical Variations of Vertebrobasilar Artery are Closely Related to the Occurrence of Vertebral Artery Dissection-An MR Angiography Study.
Hori S, Hori E, Umemura K, Shibata T, Okamoto S, Kubo M, Horie Y, Kuroda S.
J Stroke Cerebrovasc Dis. 2020 Jan 30 [Epub ahead of print]
PMID: 32008922
Abstract
GOAL: Intracranial arterial dissection is a major cause of ischemic stroke and subarachnoid hemorrhage in relatively young patients. We assessed the hypothesis that the tortuosity of the vertebrobasilar artery is associated with the occurrence of vertebral artery (VA) dissection, using MR angiography (MRA).
MATERIALS AND METHODS: This study enrolled 43 patients with VA dissection, and 63 age- and sex-matched healthy subjects were used as the controls. MRA was employed to evaluate the presence of dominant VA and the lateral shift of vertebrobasilar junction in both groups. The VA diameters were considered different when the difference was greater than .3 mm. These anatomical variations were divided into 3 types: Type 1 (vertebrobasilar junction within 2 mm from the midline), Type 2 (>2 mm-lateral shift of vertebrobasilar junction to the ipsilateral side of the dominant VA), and Type 3 (>2 mm-lateral shift of vertebrobasilar junction to the contralateral side of the dominant VA).
FINDINGS: The presence of dominant VA and the lateral shift of vertebrobasilar junction were more prevalent in patients with VA dissection than in the controls (OR: 3.46, P = .013, and OR: 4.51, P = .001, respectively). The lateral shift of vertebrobasilar junction was classified into Type 1 (n = 6), Type 2 (n = 13), and Type 3 (n = 17) among patients with VA dissection, while into Type 1 (n = 20), Type 2 (n = 8), and Type 3 (n = 7) among the controls. Type 3 predominance was observed in patients with VA dissection (P = .02).
CONCLUSIONS: Anatomical variations of the vertebrobasilar artery may play an important role in the occurrence of VA dissection.

関連記事

  1. ニューロサイエンスの旅 Vol.47
  2. 「Brain Ischemia Night in Toyama」…
  3. 富山大学脳神経外科同門会「創志塾」忘年会2018
  4. 第90回日本脳神経外科学会・中部支部会
  5. 富山紀行 Vol. 1
  6. 第100回富山県脳神経外科医会を迎えて
  7. Loftus教授ご来訪
  8. 富山大学附属病院・包括的脳卒中センター開設記念市民公開講座
PAGE TOP